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(When you react to food...an allergy or an intolerance continued)
by Tish Richardson PhD.

Food intolerance

While the incidence of food allergy remains relatively very low, albeit with recent notable increases in the incidence of allergies to foods such as peanuts and sesame seeds, the incidence of the second form of food sensitivity, namely food intolerance, is far more widespread and, unlike food allergies, is prevalent amongst adults.

Unfortunately, the term ‘food intolerance’ is often confused and interchanged with the term ‘food allergy’—but as mentioned above, the pathways of these two reactions are, however, very different. Their differentiation is important to ensure the correct diagnosis, in understanding what and how the food is affecting you and, importantly the ongoing management to optimise your health and well-being in both the short and long term. Since, in many cases of food intolerance there is no immune system involvement, no simple test such as the blood or skin prick test used in diagnosing a food allergy, is available to simplify diagnosis of a specific food intolerance.

Given that the symptoms of food intolerance are usually more vague than those resulting from a food allergy, they are often confused with other medical problems. For example, symptoms commonly associated with food intolerances can range from a recurrent feeling of ‘just being off it’ or continual tiredness, to headaches, sleep and concentration disturbances, stomach ache or distension, diarrhoea or irritable bowel syndrome, eczema, asthma, joint pain, depression or behavioural problems to name but a few. In most cases food intolerance is initially suspected but diagnosis usually starts with investigations to rule out any medical condition that could be the cause of the presenting symptoms. Obviously, the test results will be negative—and for those people with a food intolerance in whom the reaction mirrors that of an allergic reaction, the return of a negative allergy test is all the more confusing.

Once a medical cause has been eliminated, a food intolerance might just then be suspected and diagnosis at this stage might seem quite simple—just eliminate any suspect food from the diet. But in reality this can be quite complex—in the absence of simple tests, where to start? Often there is no clear pattern to the symptoms to enable pinpointing a food, more than one food may be problematic with different foods causing different reactions. The onset of the reaction may be delayed by up to 20 hours or more, and may not even be triggered if only small amounts of the food are eaten or unless it is eaten on consecutive days. Identification of the offending food suddenly becomes all the more complex.

So which foods most commonly result in a food intolerance and what in the food is responsible for the reaction? The cause can be either a substance that occurs naturally in a food or one of the myriad of artificial additives. For example, there are foods that naturally contain a high level of certain chemicals, such as salicylates or glutamates, monosodium glutamate including (MSG). The latter, for example, is found in significant levels in foods such as tomatoes, corn, mushrooms and parmesan cheese. Or, alternatively, the chemical may be added by a food manufacturer to enhance some aspect of the food, be it its colour (artificial colours), shelf life (preservatives), flavour (flavour enhancers—such as MSG, additive 621), etc.

In addition to these chemically-evoked food intolerances, other naturally occurring components of foods can elicit food intolerances, perhaps two of the best known of which are gluten intolerance and lactose intolerance. These again have very different physiological bases.

It is now estimated that as many of 1 in 250 Australians cannot tolerate gluten, one of the proteins found in wheat and other grains (such as rye, barley and spelt). In many gluten intolerant individuals, ingestion of this protein leads to marked changes in the structure of the lining of the gut wall (coeliac disease), which in turn leads to malabsorption of nutrients, the loss of some digestive enzymes and a raft of other symptoms. Another well-recognised effect is the development of in an itchy skin condition called dermatitis herpetiformis.

Lactose is the naturally occurring sugar that is found in dairy products.  Lactose intolerance results from a deficiency of the enzyme lactase in the intestine; lactase is responsible for the digestion of the milk sugar prior to absorption. The lack of ability to digest the milk sugar typically results bloating, gas, diarrhoea, stomach discomfort and pain.

These intolerances will be discussed in more detail in sections on ‘The Gluten-free Diet’ and ‘Dairy and Lactose Sensitivities’.

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